Premature Ejaculation Vasovagal Syncope
zendoc / April 2023 (304 Words, 2 Minutes)
Decreased heart rate variability (HRV), which reflects the ability and balance of the autonomic nervous system, can cause or worsen premature ejaculation and vagus nerve syncope.
Vagus syncope (neurocardiogenic syncope) is when the sympathetic/parasympathetic nerves are out of balance, and the heart rate drops sharply as the vagus parasympathetic nerves rise sharply due to rebound, resulting in nausea and fainting. That’s why the beta sympathomimetic inhibitor propranolol is sometimes used as a prophylactic treatment.
Premature ejaculation and panic attacks (panic) cannot be explained simply by the operation of the autonomic nervous system, but the work of the brain, the central nervous system, is important. When the brain quickly becomes agitated or causes heightened anxiety, physical symptoms include heart palpitations, sweating, tremors, shortness of breath, and blurred vision, which are the functions of the autonomic nervous system. These autonomic symptoms from the peripheral nervous system increase brain excitement and anxiety as they become aware of this, further encouraging premature ejaculation and panic.
When anxiety pressure is felt in the brain center before panic disorder or performance anxiety panic begins in earnest, and physical autonomic symptoms are not yet severe, the use of sympathomimetic inhibitors such as Indenol may help control symptoms. Although the autonomic nervous system is peripheral, the vagus nerve affects the central nervous system backwards, lowering physical symptoms and brain anxiety, and also playing a role in preventing the vicious cycle between the peripheral and central spine. Of course, if not only the brain center but also the autonomic nervous system has already reached the stage where positive feedback is activated and it is impossible to stop the runaway, Indenol will not help.
Premature ejaculation can have a variety of causes, and currently the most standard symptomatic drug works to control excitability in the brain by giving a short-term boost to serotonin lowered by dapoxetine. Ejaculation consists of two stages, emission and expulsion, and when HRV drops, the sympathetic nerves are rapidly hyperactive in the release stage, and it is easy to launch without control.
The use of indenol to prevent rapid hyperactivity of the sympathetic nerves in the peripheral stage in premature ejaculation has little effect in delaying ejaculation. Raising HRV by raising serotonin through breathing or dapoxetine helps control ejaculation and delay ejaculation. Conversely, in seborrhea, ephedrine, a sympathomimetic agent, is sometimes used to promote ejaculation, but the effect also varies from person to person. Sexual arousal is a very intense stimulus in the brain center and occurs rapidly, so the peripheral autonomic nervous system may be an auxiliary part.
Measuring HRV, a barometer of balance and ability of the autonomic nervous system, has become a routine task, and smartwatches are equipped with a breathing training app to increase HRV by default. Zendoc is creating an app that can train not only the peripheral autonomic nervous system but also the anxiety of the brain center through more specialized understanding and application.